Overweight and obese people who take a high-dose of supplementary Vitamin C daily may get some of the cardiovascular benefits of exercise without the exercise, new research has found. In a small trial that recruited sedentary adults who were overweight or obese, study participants who took 500 milligrams of Vitamin C daily saw equal improvement in blood vessel tone — a key measure of cardiovascular health — as did those who took up a three-month regimen of brisk walking five to seven times a week, investigators at the University of Colorado at Boulder reported. The study's small size — 15 subjects got the walking treatment, while 20 took the Vitamin C supplements — may also limit the uptake of its findings by public health officials, who have struggled, with limited success, to get sedentary Americans off the couch. Some 4 in 10 American adults are thought to be entirely sedentary. But the study's invasive measures of "endotheli...