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SMART BANDAGE THAT GLOWS




SCIENTISTS    have  designed   a   paint  on  see-via,  smart   bandage  that   glows  to  indicate  a  wound's   tissue    oxygenation    concentration .



The   smart   bandage  created by  an  international , multidisciplinary  group  of  researchers  ,led  by  assistant professor Connor L.Evans  at  the   Wellman  center  for  photo medicine   of   Massachusetts   Basic  Hospital(MGH  )  and  Harvard   Healthcare  College(HMS ,  provides   direct,  noninvasive    measurement  of   tissue  oxygenation   by  combining  three   simple  , compact   and  economical  components ;a  bright  sensor  molecule   with  a  lengthy   phosphorescence   lifetime and  proper  dynamic  range  a bandage   material   compatible  with  the  sensor   molecule   that  conforms  to  the  skin's surface    to  form  an  air tight  seal    and  an   imaging   device  capable  of   capturing  the    oxygen-  dependent   signals   from  the  bandage  with  higher  signal -to-noise  ratio . 
HOW  DOES  IT  WORKS- The bandage  is  applied  like  a  viscous   liquid   which  then  solidifies  in  less then  a  minute .After  it has  dried , a  transparent   barrier  layer  is  then  applied  a top  it.to  protect  the  film  and  slow  the  rate  of  oxygen  exchange   between  the bandage  and  the  room   air, making  the  bandage  sensitive  to oxygen  coming  only  from  inside  the  skin.Oxygenation   is   very  important  in  dealing  with  wounds.Oxygen  play  an   important   role  in  wound  healing , as  it   essential   to  biological  functions   such  as  cell  proliferation,immune   responses and  collagen  synthesis. 
The   bandage  is  quite  easy    and  painless  to  take off.The  bandage  comes  off   easily -the  liquid  bandage   dry  into  a  tacky   gel   underneath  a  plastic   layer 'the  entire  bandage  comes  off   with  simple  peeling .
The  key  to  the  glow   is  phosphorous -an  element   which  can  absorb  light wavelength  and  then  release them,glowing.The  more  oxygen  the   stronger  they  glow.How  brightly  the  phosphorescent  molecules    emit  light depends on  how  much  oxygen  is  present ,as  the   concentration  of  oxygen  is   reduced ,  the  phosphorous  glow   both  longer   and  more  brightly.
The   last  element  is  camera -based  read out device   which  does  two  things :Triggers  the emission  of  phosphorous   inside  the  bandage  and   then  monitors  the  phosphorous   emission.
Depending   on  the  Camera's   configuration,  we  can   measure  either  the  brightness  or  color    of the  emitted  light  across  the  bandage  or  change in brightness   over  time.Both  of  these  signals  can be  used   to   create   an  oxygenation  map.  
They  are  creating  brighter  sensor molecules  to  strengthen   the  bandage's    oxygen  sensing  efficiency.' 
Now, they  are  also  working   on  revealing   other parameters   aside   for  oxygenation-such  as  PH,bacterial   level  and  specific  disease  marker.
The  application   of  such  bandage  quite  straightforward  - they  could  monitor  severe  wounds   and  burns,particularly  in  ischemic(Restricted  blood  supply) conditions ,postoperative    monitoring   of  skin  graft  or  flaps     and  this  can  be done   cheaply  and  in  a  non  invasive   way.That  makes it   more  better.
GLOWING  BANDAGE
CONOR  EVANS
 




          
  

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